Product Name: ANTI-TYROSINE HYDROXYLASE ANTIBODY (Pending Permit)
Product Code: P60101-150
Pack Size: 150 µL
Host Species: Sheep (Polyclonal)

Description:
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001; Dunkley et al., 2004).

Physical State:
Liquid; Buffer contents: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50% glycerol

Storage/Stability:
Stable at -20 °C for at least 1 year.
For long term storage -20 °C is recommended

Purification Method:
Prepared from sheep serum by affinity purification using a column to which immunogen was coupled. The antibody is predominantly of the IgG1 subclass.

Shipping Conditions:
Domestic: Blue Ice
International: Blue Ice or Dry Ice

Immunogen:
Native rat tyrosine hydroxylase, purified from pheochromocytoma

Species Reactivity:
All mammalian and at least some non-mammalian forms of the enzyme in
Western blots and in IHC/IF.

Recommended Antibody Dilutions:
WB, IF, IHC: 1:1000

Specifications
Physical State: Liquid; Buffer Contents: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50% Glycerol

Product Overview